Designed by Renzo Piano, the 2,600 m2 building combines a façade dating from the 30s (the former Palais de la Foire de Lyon) with the modernity of a volume built in red brick.
The façade dating from the 30s gives onto the Tête d'Or Park, while the glass walls open onto the inner street of the Cité Internationale, facing the UGC cinema. The public may pass freely through the museum when it is open.